Autoimmune Myositis Cohort Study

Research Leaders: Professor Merrilee Needham and Professor Francis Mastaglia

Interested in this research, contact Dr Susan Herrmann 

Researchers and patients interested in this condition are invited to inquire about this cohort study. The inflammatory myopathies are a group of conditions that involve chronic muscle inflammation (myositis). The cause is unknown and while understood to be immune-mediated conditions, the underlying pathological mechanisms of myositis are unclear.

The estimated prevalence of myositis in Australia is of the order of 140 cases per million. Myositis is classified according to distinct clinical symptoms, tissue pathology and biomarkers but there are common properties between the classifications, e.g. muscle weakness and inflammation.

Diagnostic precision is important to ensure that clinical management and treatment is appropriate and that patients receive the right education and support. New treatments available in clinical trials require that patients are carefully classified pre-trial to enable outcomes to be accurately assessed.

Neurologists in IIID have established an observational cohort study to better understand the inflammatory myopathies and improve clinical care. Over time the study will collate clinical information and take advantage of the latest research methods to study immunity.